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While you should always consult your healthcare provider before starting a new supplement, it may be wise to avoid or closely monitor astaxanthin use if you fall into one of the following categories: People taking blood pressure or cholesterol medications Astaxanthin may modestly lower blood pressure and LDL cholesterol in some studies.29 42 If you already take antihypertensive or statin drugs, combining them could theoretically amplify these effects

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28,29,516 Specifically, IGF-1 treatment results in increases in synaptic protein levels and activation of signalling pathway proteins and enhances cortical excitatory synaptic transmission and dendritic spine density