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Cells were transfected with siEPAC1 or siEPAC2 and pooled siRNAs at 0.1 nM concentration each using Lipofectamine RNAiMax transfection reagent according to manufacturers instructions

PMID: 68 MihalasBPRedgroveKAMcLaughlinEANixonB

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Metformin-induced apoptosis facilitates degradation of the cellular caspase 8 (FLICE)-like inhibitory protein through a caspase-dependent pathway in human renal cell carcinoma A498 cells

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Local glucose elevation activates pyroptosis via NLRP3 inflammasome in ovarian granulosa cells of overweight patients