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Higher doses are also more likely to cause GI symptoms, such as bloating, gas, and diarrhea, because excess creatine may not be fully absorbed and can linger in the digestive tract, drawing in water and contributing to these uncomfortable side effects

Skin texture was measured by a PRIMOS CR apparatus (anterior forearm) and tape-stripping of the SC (facial region) was analyzed for protein analysis and lipid/ceramide content using a ACQITIC UPLC system

The fast injury healing resource page provides additional context on recovery optimization

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J Sci Food Agric 33:795801 Caruso G, Fresta CG, Martinez-Becerra F et al (2017) Carnosine modulates nitric oxide in stimulated murine RAW 264.7 macrophages