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Alkynylated probes derived from senolytic chloroacetamides A detailed description of the synthesis of alkynylated probes derived from senolytic chloroacetamides and the NMR spectra of the synthesized probes is provided in Supplementary Note 1

If the benefits of fibrate therapy are indeed mitigated by fibrate-induced betaine deficiency, the use and safety of supplementing patients with betaine would need to be considered (127)

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