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The PK profile of 7,8-DHF given by IP injection in our neonatal mice differs from the oral 7,8-DHF PK profile in adult mice reported by Liu and colleagues (Liu et al., 2013)

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Smit EF, et al

This is precisely why a one-size-fits-all answer is impossible, and frankly, irresponsible for anyone to give

Always consult a trusted healthcare practitioner before making changes

Understanding these mechanisms and their clinical implications is essential for developing targeted interventions that improve treatment outcomes and combat resistance in leishmaniasis