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It tends to be worst during the first few weeks and during dose increases

-(Free-Form Base) 3 g (3,000 mg)

Can medical weight loss programs help with weight maintenance

Ossenkoppele, R., van der Kant, R

Funding This work is supported by research grants from the Canadian Institute of Health Research (MOP 201803PJ8) and the Alzheimers Association (PTC-18-543823) and made possible by Part the Cloud, as well as the Alzheimer Society Research Program (ASRP #21-11)

Large clinical trials have not identified bone loss as a significant adverse effect, though the weight loss these medications produce may indirectly affect bone density in some individuals