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Indeed, Kang reported that human volunteers who ingested supratherapeutic doses of APAP (80 mg/kg) excreted dramatically lower amounts of APAP oxidative (CYP450) metabolites in urine when treated with fomepizole ( Figure 21 )

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Blood Pressure Fluctuations: BPC-157 interacts with the nitric oxide system, which regulates blood pressure, and reports of temporary fluctuations (spikes or drops) immediately after administration have been noted in anecdotal accounts

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