cagrilintide retatrutide combination trial Once-weekly for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 cagrilintide semaglutide trial We – www Retatrutide vs CagriSema: The Battle

It's massive, and it extends far beyond the number on the scale

Promote satiety: They act on appetite-regulating centres in the brain to increase the feeling of fullness after eating

Key points for patients: GLP-1 therapies help clear skin and reduce painful, swollen joints Obesity makes PsA harder to treat, so weight loss from GLP-1 meds helps In studies, patients on GLP-1s had fewer flares, less pain, and felt better overall

Research points to GLP-1 as having a role in entraining the circadian rhythm of insulin release in the pancreas

GLP-1 is of relevance to appetite and weight maintenance because it has actions on the gastrointestinal tract as well as the direct regulation of appetite

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