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By targeting all three receptors, retatrutide is designed to produce a more pronounced effect on body weight and blood glucose regulation, though whether this translates into superior long-term clinical outcomes remains to be confirmed in Phase 3 trials

Frontiers in Pharmacology, 15 , 1416985

This can be managed similarly to diarrhea by staying hydrated and eating a balanced diet thats high in fiber

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The timeline for availability: Lilly will likely price retatrutide at or above Zepbound levels, given the superior efficacy data