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This review article will introduce some of the small molecule drugs that are currently receiving significant attention: Orforglipron Orforglipron is an oral small molecule GLP-1RA developed jointly by Eli Lilly and Chia Tai Tianqing Pharmaceutical Group

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In NSCLC, HCQ shows promise as both a chemosensitizer and immunomodulator, potentially by reducing lysosomal drug sequestration and boosting CD8+ T-cell responses (83)

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