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The cell lines, however, lose their BBB characteristics the more they are passaged, decreasing tight junction and transporter expression
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Moreover, FOXO4-DRI was used to selectively induce apoptosis of senescent fibroblasts in both keloid fibroblast and organ culture senescent models, showing potential as a treatment that targets the senescence and apoptosis resistance observed in keloid fibroblasts
Republic of Korea Patent Application
Energy 2 , 021004 (2020)
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