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Additionally, an antioxidant-rich diet is essential, with at least five servings of fruits and vegetables daily

This is exactly why these medications should be used as part of a comprehensive program that includes nutrition education, behavioral support, and a long-term maintenance strategy

However, because it improves insulin sensitivity, diabetes medications may need to be adjusted

For a long-acting peptide like tirzepatide (half-life ~5 days), this difference is clinically minor but measurable in pharmacokinetic modeling

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