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[7] [8] Diversity [edit] Two classes of thioredoxin reductase have evolved independently from a shared ancestor of the FAD/NAD(P)-binding domain superfamily (IPR036188): A high molecular weight (MW = ~55,000) type containing a selenocysteine residue in its active site has been identified in higher eukaryotes including humans

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doi: 10.1080/07373937.2010.483047 191 SaidimoradiD.GhaderiN.JavadiT

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Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals

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