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The study results indicate that the crude methanolic extract and 12-ursene 2-diketone are capable of carrying out a natural anti-inflammatory activity at sites where chronic inflammation is present by switching off the pro-inflammatory cytokines and mediators, which initiate the process

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doi: 10.1038/s41392-024-01931-z

doi: 10.3389/fimmu.2020.626812 362

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Acute Lung Injury Models In acute lung injury models, GHK-Cu reduces inflammatory cell infiltration, increases superoxide dismutase activity, decreases TNF- and IL-6 production, and protects lung tissue from LPS-induced injury