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In relation to obesity, genetic variants in GPX4 have been linked to obesity and inflammation in humans (38, 39), suggesting a role for GPX4 in metabolic disorders

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

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Intramyocellular lipid deposition, common in obesity but also a feature of sarcopenia, may result in part from mitochondrial dysfunction with resultant accumulation of unmetabolised free fatty acids [53]

(2013), Vitamin B12 and vegetarian diets