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Andersson, G

Reddy LH, Couvreur P (2009) Squalene: a natural triterpene for use in disease management and therapy

488498, 2018 [49] X

This fascinating development comes from a study led by Dr

100 mg/mL Usual Adult Dose for: Usual Pediatric Dose for: Additional dosage information: Usual Adult Dose for Carnitine Deficiency METABOLIC DISORDERS: Primary or secondary carnitine deficiency: Oral solution: Initial dose: 1 gram orally daily in evenly spaced divided doses (every 3 to 4 hours) Maintenance dose: 1 to 3 grams orally daily in evenly spaced divided doses (every 3 to 4 hours) Oral tablets: 990 mg orally 1 to 3 times a day, depending on clinical response Intravenous solution: 50 mg/kg as a slow 2 to 3 minute bolus or by infusion, once a day A loading dose may be given in severe metabolic crisis, followed by an equivalent dose every 3 to 4 hours (but not less often than every 6 hours) over the following 24 hours Subsequent daily doses should be in the range of 50 mg/kg or as therapy may require The highest dose administered has been 300 mg/kg

In some embodiments, the otic pharmaceutical formulation comprises between about 80% to about 99.99% by weight of the triglycerides