retatrutide liver fat reduction may be promising for because it targets appetite, weight loss, glucose control, and metabolic health at once. But “nearly clinical” still means not a guaranteed treatment, so liver labs Retatrutide: Eli Lilly's GLP-1 Triple

GLP-1 121 Q

In circumstances where patients cover the cost of treatment, where reimbursement is restricted, or when insurance coverage is limited, the financial expense may influence selection of GLP-1 RA therapy [123]

Bibcode:2020PNAS..11729959K

Reflux, nausea, or abdominal symptoms that worsen after dose escalation and do not improve with basic plan changes

Similarly, rates of stroke [110, 111], and new diagnoses and progression of cognitive impairment [168] are reduced in post hoc analyses of secondary endpoints in CVOTs of GLP-1RA in people with type 2 diabetes

This was a landmark finding because it established that a weight loss medication could provide cardiovascular protection independent of diabetes status