One of the major concerns following surgical resection specifically is local cancer recurrence and is a common problem in several types of cancer often caused by inadequate resection margins, which allows any remnant cancer cells to continue to proliferate
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DPN is related to the increase of inflammatory cells in peripheral nerves, abnormal cytokine expression, oxidative stress, ischemia ,and pro-inflammatory changes in bone marrow
Resnick HE, Bardsley J, Foster GL, et al
NAD+ (Nicotinamide Adenine Dinucleotide) is a vital molecule found in every cell of our body and is involved in various cellular processes, including energy metabolism, DNA repair, and cell signalling