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While not a medical diagnosis, it highlights the potential side effect of rapid fat loss in the face, leading to visible changes like sunken cheeks and looser skin

Polyethylene glycol (PEG) is a water-soluble inert polymer that reduces the renal clearance of the drug and prolongs the half-life, in addition to enhancing water solubility and preventing proteolysis

Convenient dosing: A single weekly subcutaneous dose is easier to stick with than daily regimens [1]

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If that happens, it may be worth considering some of the other medications approved for weight loss that are not GLP-1s