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Butterbur is so effective for reducing the frequency and severity of migraine attacks, that the American Academy of Neurology (AAN) and the American Headache Society (AHS) have recommend it as an effective treatment for migraine (Holland 2012)

J Fungi 7(9):719 Mandal SM, Chakraborty D, Dey S (2010) Phenolic acids act as signaling molecules in plant-microbe symbioses

Apart from the cosmetic angle, many also report improved energy levels, reduced inflammation, and better immune function over time

doi:10.1080/15287399409531852

Pituitary (2002) 5(3):1813.10.1023/A:1023321421760 174 TagliaferriMScacchiMPincelliAIBerselliMESilvestriPMontesanoAet alMetabolic effects of biosynthetic growth hormone treatment in severely energy-restricted obese women

Gut 63:10811091