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Published in Diabetologia (Blher and colleagues, NCT04153929), this Phase 2 trial randomized 413 adults with type 2 diabetes on background metformin to survodutide across several once-weekly or twice-weekly dose groups, to placebo, or to open-label semaglutide up to 1.0 mg once weekly

It hits one receptor, GLP1, that is a hormone that your gut releases that tells your brain that you're full

Do they enhance or impair performance

Nat Cell Biol 2008

This process releases ketones (specifically acetoacetate), which are excreted through urine and can produce a distinct "fruity," "sweet," or "metallic" smell

No obvious changes in body weight or tissue damage were observed during the 2 week observation (Fig