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In a study published in the American Journal of Clinical Nutrition , researchers gave healthy adults 500mg of vitamin C daily and measured a rise in red blood cell glutathione of nearly 50% within two weeks, compared with baseline (Johnston et al., 1993)

Ultrasound measurements showed statistically significant increases in dermal thickness in the treatment group versus placebo

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J Biol Chem 278:4597845986 [DOI] [PubMed] [Google Scholar] Tanowitz M, Hislop JN, von Zastrow M

the control group), but no change in shank muscle weight