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The protein band was cut out and run in liquid chromatography coupled with tandem mass spectrometry shotgun proteomics by the University of Texas Biological Mass Spectrometry Facility

The therapeutic application of the PBN mechanism in MI/R involves three key strategies: (1) Targeted enzymatic therapy employing the Targ-CD39 fusion protein, which binds activated GPIIb/IIIa to enhance capillary density in infarcted myocardium while concurrently preventing thrombosis and vascular occlusion [45, 46, 48]

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