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Choline diet and its gut microbe-derived metabolite, trimethylamine n-oxide, exacerbate pressure overload-induced heart failure

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therapies are largely symptomatic and directed at palliation rather than correction of the underlying immune dysfunction

Satellite cell activation: Skeletal muscle has a population of stem-like satellite cells that, when activated, differentiate into myoblasts and fuse with existing muscle fibers literally adding new nuclei and increasing muscle fiber density

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