Uh, these studies are where we watch group of patients and subjects and look at what theyve been exposed to just in everyday life, in this case, GLP-1 agonists, and then see if they have increased risks of a certain outcome, in this case, hair loss
362 In an experimental study in which osteoclast formation and bone resorption were induced in mice through lipopolysaccharide (LPS) administration, researchers discovered that simultaneous treatment with exendin-4 resulted in a significant decrease in the number of osteoclasts, the proportion of bone resorption pits, and the levels of the bone resorption marker CTX compared to injection with LPS alone
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Ferreiro E, Lanzillo M, Canhoto D, Carvalho da Silva AM, Mota SI, Dias IS, et al
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For patients and clinicians, this matters because it changes how we think about outcomes