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Consistently, when cells were subjected to cystine starvation in the presence of 6-diazo-5-oxo-L-norleucine (DON, a selective GGT inhibitor), there was a markedly higher accumulation of extracellular GSH (Fig

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doi:10.1007/s00213-013-3340-1

Similarly, HCT116 cells treated with the pan-Raf kinase inhibitor AZ628 (~100-fold higher than the IC 50 ) also yielded a small percentage of DTPs, amounting to ~0.70% of the starting population ( Figures 1B, D, E )

Urological management Urogenital erosions may persist for several weeks and any resultant scarring can lead to permanent urinary or sexual dysfunction [36], [37]

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