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In CHO-SNAP-GLP-1R cells, a small but reproducible increase in surface downregulation potency was seen with exendin-asp3, as measured by cell surface ELISA (Supplementary Fig

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Access and reimbursement will also vary, shaped by each countrys health policies and ongoing reviews of cost-effectiveness for obesity treatments

1 Introduction Until recently, the worldwide increase in obesity, characterized by a body mass index (BMI) exceeding 30 kg/m 2 , was widely considered an inevitable trend with limited hope for meaningful advances in pharmacological treatment