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Preliminary findings in animal models highlight changes in body composition, energy expenditure, and insulin sensitivity

Long-term administration in mice inhibited development of leukemia by 6-fold and reduced total spontaneous tumor incidence, with no increase in cancer risk despite telomerase activationaddressing theoretical concerns about uncontrolled proliferation

JCI Insight 8 , e170767 (2023)

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This process can also foster long-term immunological memory resulting in sustained anti-tumor effects