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Researchers have also questioned whether the increase in cognitive or dietary restraint seen with GLP-1RAs reflects healthier control over eating or a more rigid form of food restriction that could prove harmful

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Meanwhile, employers are still grappling with unknowns associated with GLP-1 drugs, namely side effects and still-emerging long-term clinical studies, and the effectiveness of cost control tools like prior authorization and step therapy. But as evidence of the benefits of using the drugs for weight loss continues to grow, along with increased employee demand, it looks like many employers might add coverage

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This knowledge contributes to the expanding paradigm that GSH plays diverse roles in the pathogenesis of intracellular bacteria and represents a potential target for host-acting therapeutics

Some of the side effects of using GLP-1 drugs include nausea, constipation and diarrhea