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Neuroinflammation Level of Evidence: Moderate preclinical evidence ALC exerts significant anti-neuroinflammatory effects through multiple mechanisms

But the same 2025 review that catalogs those effects also underscores that only three human clinical trials have been published and that the compound remains investigational, with regulators having flagged it precisely because human safety and efficacy are not established

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Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development - A review