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(2017) proposed that biases resulting from independently applied methodologies could be alleviated by the utilization of OS indices that encompass multiple markers pertinent to the objectives of the clinical study and its implications for clinical practice

Therefore, future research must prioritize improvements in longitudinal studies to address differences between rodent and human autoimmunity progression during the asymptomatic first and second phases of T1D pathogenesis

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Compared to healthy controls, a significant increase in demyelinated area was observed during the acute phase of the disease and even aggravated during relapse (Fig

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