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J Endocrinol 29(3):362366 Shang, Y., Siow, Y., Isaak, C., and Karmin O, (2016)

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The daunting task of clinical validation cannot be overlooked

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A secondary issue is saturation kinetics

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Preliminary evidence suggests NAD-boosting compounds (nicotinamide riboside, NMN, niacin) may improve mitochondrial function and insulin sensitivity in rodent and some human studies, but effect sizes remain modest

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doi: 10.3390/antiox14020155 198 Martnez-FerriEForbes-HernandezTYCervantesLSoriaCBattinoMArizaMT

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