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Given the significant effect of time and our interest in the effects of the IF-P group, we prepared a GLM with age, sex, BMI, and time as covariates and corrected for FDR (Figure 5A)

Important safety considerations for transdermal patches: Avoid applying external heat (such as heating pads, hot water bottles, electric blankets, or prolonged sun exposure) to the patch area, as this may increase drug absorption and side effects Do not cut patches or apply additional adhesives unless specifically instructed to do so Wash hands thoroughly after handling patches to avoid transferring medication to eyes or mucous membranes For patients currently using licensed injectable GLP-1 receptor agonists, continue to follow the administration instructions provided in the PIL and by your healthcare team

The occurrence of protein oxidation is marked by substances such as protein carbonyls, advanced glycation end products (AGEs), oxidized LDL (ox-LDL), and advanced oxidation proteins (98)

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