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Have a baseline BMI (prior to any weight-loss treatment) of 30 or 25 with one or more previously diagnosed conditions: Controlled Type II Diabetes, Sleep Apnea, High Cholesterol, High Triglycerides, Prediabetes, High Blood Pressure, Heart disease, Osteoarthritis, Polycystic Ovarian Syndrome (PCOS), Non-alcoholic Fatty Liver Disease (NAFLD), Cardiovascular Disease, Gastroesophageal Reflux Disease (GERD), Depression, Anxiety, Weight-Related Psychosocial Distress, Stroke, Coronary Artery Disease, Metabolic Syndrome, Insulin Resistance, Body Pain, Infertility, Hypothyroidism, Sexual Dysfunction

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With total choline, the difference was driven by lower levels in long COVID compared to the HC group (F = 17.692, p = 0.0002)

It is also being studied for treating type 2 diabetes, with significant improvements seen in blood sugar control alongside meaningful weight loss