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A good approach: use shakes to fill gaps when food isn't working, not as the primary source

Stability over time also affects effective concentration

doi: 10.7759/cureus.45964

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation

That said, inconsistencies in dosing can lead to underwhelming results or mild systemic side effects such as headaches or nasal irritationparticularly in compounded or off-label versions