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While these therapies offer strong glycemic control, meaningful weight loss, and even cardiovascular benefits, many patients stop treatment earlier than expected

doi:10.7326/0003-4819-156-10-201205150-00004

Int J Exp Pathol (1998) 79(6):34757

Think of this classification as a yellow warning light rather than a red stop signits not proven dangerous, but its not proven safe either

For example, impairments in insulin receptor signaling within the hippocampus and prefrontal cortex can disrupt synaptic plasticity and neurotransmitter balance, potentially leading to cognitive deficits and mood disturbances associated with depression [95]