The authorization was based on the outcome of the SOUL clinical trial
Both medications use gradual dose increases to reduce side effects
Still, fatigue hits like a wall
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What Im afraid of happening at the end of this week when the deadline hits is that patients and providers wont have access to the medications they need, and they will be financially impacted as they move forward because of this. The Outsourcing Facilities Association filed lawsuits against the FDA about the sudden removal of tirzepatide and semaglutide from the drug shortage list, but the judge in both cases ruled to allow the FDA plan to block compounded products to continue
[10] [11] While the primary therapeutic effect targets glucose regulation, the presence of these receptors in regions associated with mood and cognition raises theoretical questions about broader effects, though human evidence for direct personality changes is lacking