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Chao CL, Tsai HH, Lee CM, Hsu SM, Kao JT, Chien KL, Sung FC, and Lee YT (1999b)

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Despite these promising perspectives, no unequivocal benefits have been established since in a recent large intention-to-treat analyses, acarbose was associated with a higher risk of development of any cardiovascular event, heart failure, and ischemic stroke compared to metformin [22]

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