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It may also act as an anti-inflammatory drug owing to its beneficial effects in animals with inflammatory conditions (Yuan et al., 2014)

249 In the brains of transgenic parkin-deficient mice, the inhibition of p53 caused by parkin deficiency increases XBP-1 expression, which in turn promotes DJ-1 expression by binding and transactivating the DJ-1 gene promoter

The entire analysis was performed using pyEMMA 66 freely available at github ( Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article

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