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Glutathione enzymes act as built-in defenders against this process

(2016) Intravenous glutathione for skin lightening: Inadequate safety data

J Biol Chem 294:48434853 Tanaka Y, Gleason CE, Tran PO, Harmon JS, Robertson RP (1999) Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

However, excessive inhibition of autophagy may lead to the accumulation of cellular debris, which could be detrimental to neuroprotection

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