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Thus, the formation of the dehydro-alanine glutathione species (that observed at m / z 272 in the spectra of glutathione-bound metals) is a key to the possible explanation of the ability of metals such as lead and cadmium to generate oxidative stress in cells without the necessity that the electrochemically silent metal itself change its oxidation state

It is noteworthy that NAC treatment also enhanced insulin sensitivity in chow-fed mice (Fig

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That might be an oversimplification, or at least, very much dose and use-dependent