The clinical trial data provides averages, but individual responses vary enormously based on starting weight, metabolic health, adherence, dietary choices, physical activity, and genetic factors
Its important to note that SGLT-2s have been shown in both the EMPA-REG and CREDENCE trials to have a greater initial reduction in estimated GFR (eGFR) during the first ~3 weeks than placebo, but the subsequent decline in eGFR was slower than placebo as the trials continued, showing renal protection benefits
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Physician supervision ensures the dosing is appropriate for your health profile and any medications you may be taking
That meant she could only take care of 30 patients per month and she had a lot more patients taking compounded tirzepatide than that
2016 Sep 28;22(36):813748