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Although glucagon action is primarily liver specific, glucagon receptors have been reported to be present in membranes of human adipose tissue (83), suggesting that direct action of glucagon likely plays an important role in regulating human, as well as rodent, lipolysis

Vegetarians, vegans, those with gastrointestinal conditions, or individuals on certain medications like metformin or acid blockers are also at greater risk

doi: 10.1186/s12940-018-0366-1 217 HuYDingGLvCZhangQZhangYYuanTet al

10.1016/j.jpeds.2016.02.070 30

20 CardonaD.RomanP

DISCUSSION SUPPLEMENTARY MATERIAL Supplemental Table S1 Supplemental Table S2 Supplemental Table S3 Supplemental Table S4 Supplemental Table S5 Supplemental Fig S1 Supplemental Fig S2 CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported