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Pharmacokinetics (ADME) Absorption Well absorbed orally Rapid onset Distribution Highly protein bound (~99%) Metabolism Mainly hepatic metabolism Glucuronidation is significant Half-life About 23 hours But effect lasts longer due to enzyme inhibition Excretion Mainly via bile/feces Some renal excretion --- 5

Gallstones which obstruct the ducts can also lead to a secondary condition called hydro cholecystitis (gallbladder hydrops), where the gallbladder is distended with mucus, water, or clear liquid content instead of bile. How do you treat gallbladder disease

Robert Popovian 01:53 Thats a great question Conner

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About 6 out of every 10,000 in the SGLT-2 inhibitor group

That's why we're excited to introduce Biocare Beverages , a new product specifically designed to complement GLP-1 RA medications like semaglutide