[55] found that luteolin could reverse the up-regulation of IL-1, IL-6, and TNF- in the hippocampus and prefrontal cortex of mice with noise-induced depression while improving synaptic plasticity impairments by inducing BDNF expression

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IGF1 indirectly increases DNA repair by 50% through increasing the p53 dependence in the p21, while inhibition IGF1R by siRNA in human prostate cancer cells enhances the sensitivity of ionizing radiation to SSBs and DSBs (Clark et al., 2005)
Glutathione Increases energy Improves skin and scarring Detoxifies the liver and cells DR
The metabolic plasticity of cancer is not restricted only to cancer cells but extends throughout the TME (184, 185), as seen in CAFs that secrete lactate, lung mesenchymal-derived cells that transfer lipids, suppressing the functioning of NK cells, and arginine-depleting collagen-producing TAMs, leading to the suppression of CD8 + T cell functions