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It is postulated that DM-induced oxidative damage may be more significant in erythrocytes than in other cells, due to their high content of iron and polyunsaturated fatty acids, as well as their role as oxygen transporters, with a high degree of exposure to free radicals [320]

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Regular monitoring of cardiovascular health markers, such as blood pressure and lipid profiles, is essential to assess the effectiveness of tirzepatide and make any necessary adjustments

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OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand