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After 70 days of treatment, CMCS reduced hepatic fat as assessed by MRI by 10% compared with the placebo

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To achieve this, we designed an inducible system that upregulates glutathione production by expressing glutathione synthetase, glutathione reductase and glutathione peroxidase in the presence of ROS

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Al Rifai M, Silverman MG, Nasir K, Budoff MJ, Blankstein R, Szklo M, et al

Additionally, a significant stepwise rise in Lac-Phe levels is detected as plasma metformin concentrations increased across quartiles