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Bensaad, K., et al., TIGAR, a p53-inducible regulator of glycolysis and apoptosis

Important context: no supplement is a substitute for a calorie deficit and consistent training

They are frequently mentioned together because both have demonstrated wound-healing and tissue-protective effects in animal models, but they are structurally and mechanistically distinct molecules

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On the other hand, creatinine is a chemical waste product that is produced by muscle metabolism

Sports Medicine (Auckland, N.Z.), 30 (3), 155-170