Whats more, over a dozen potential new GLP-1 RAs are being developed [archived link]
Some people notice patterns like persistent fatigue, feeling unsatisfied after meals, slower recovery from physical activity, changes in hair or nails, and simply eating much less than before when protein intake drops
Wegovy, which seemed to sail smoothly, hit a snag after announcing follow-up data in May 2022
A systematic analysis reported that using metformin alongside GLP-1RAs in type 2 diabetes management increases the risk of nausea and vomiting
The third limitation is that there may be the potential for numerous indirect effects or confounding
Ozempic, approved for type 2 diabetes) and tirzepatide (Zepbound, approved for weight management