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Early records of pellagra followed the widespread cultivation of corn in Europe in the 1700s (23)

SiddharthJChakrabartiAPannerecAKarazSMorin-RivronDMasoodiMet al

Further, experimental studies, in turn, should evaluate in more controlled settings, several aspects: (i) the role of acute and chronic PE in the molecular mechanisms that are underlying the onset of the disease and thus, test whether these positive changes in mitochondria, EAS enzymes and IS modulation reflects on the epidermis and in the melanocytes from vitiligo patients